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Activity Number: 184
Type: Invited
Date/Time: Monday, August 7, 2006 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #304993
Title: Application of Threshold Regression in Analyzing Lung Cancer Rates in Women
Author(s): Mei-Ling T. Lee*+ and Bernard Rosner
Companies: The Ohio State University and Harvard Medical School
Address: Biostatistics Division, School of Public Health, Columbus, OH, 43210,
Keywords: lung cancer ; threshold regression ; non-proportional hazard models ; proportional hazard models ; hazard ratios ; longitudinal survey data
Abstract:

On the basis of longitudinal survey data from the Nurses' Health Study, we investigate women's lung cancer rates with respect to smoking exposure using threshold regression methodology. Smoking history, smoking status, and pack-years were used to measure smoking exposure. We calculate age and exposure-specific lung cancer rates and obtain hazard ratios for smokers and nonsmokers. We compare our results with those provided by a proportional hazards approach.


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