JSM 2005 - Toronto

Abstract #304807

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 149
Type: Luncheons
Date/Time: Monday, August 8, 2005 : 12:30 PM to 1:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #304807
Title: Metaanalyses: Past, Present, and Future
Author(s): Charles Anello*+
Companies: U.S. Food and Drug Administration
Address: CDER, North Bethesda, MD, 20852-3122,
Keywords:
Abstract:

Metaanalyses has a long history as a statistical methodology. The application of metaanalysis to the fields of clinical trials and epidemiology is relatively new. We will explore a little of this history and the origins of this idea. Next, we will look at current applications of metaanalysis in the field of medicine and public health, with a focus on successful applications, and discuss its limitations. Is there a role for metaanalyses in the design and analysis of historical control and noninferiority trials? Finally, the discussion will focus on the future for metaanalysis and metaanalysts and ask the question: Should the whole idea be dropped?

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Revised March 2005