JSM 2005 - Toronto

Abstract #304625

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 74
Type: Contributed
Date/Time: Sunday, August 7, 2005 : 8:00 PM to 9:50 PM
Sponsor: General Methodology
Abstract - #304625
Title: Analysis of Longitudinal Data in Presence of Informative Observation Process with Application to Pediatric Cancer Study
Author(s): Shesh Rai*+ and Sean Phipps and Deo K. Srivastava and James M. Boyett and Jianguo (Tony) Sun
Companies: St. Jude Children's Research Hospital and St. Jude Children's Research Hospital and St. Jude Children's Research Hospital and St. Jude Children's Research Hospital and University of Missouri, Columbia
Address: 332 N lauderdale St, Memphis, TN, 38105, United States
Keywords: Joint Modeling ; Health Outcome data
Abstract:

We briefly describe a longitudinal study of pediatric cancer patients involving bone marrow transplants who are followed for quality of life measures (response process) during and immediately after the cancer treatment. In this study, longitudinal followups are incomplete on a significant proportion of patients due to many reasons. For example, data related to response process are missing due to scheduling conflict or due to death. Data missing due to death (observation process) cannot be treated as random. We model these two processes jointly. We study the properties of our method through a simulation study and apply this to the pediatric cancer study.


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Revised March 2005