JSM 2005 - Toronto

Abstract #304210

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 482
Type: Contributed
Date/Time: Thursday, August 11, 2005 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #304210
Title: The Impact of Transformation in Quantitative Genetics Analysis
Author(s): Mariza de Andrade*+
Companies: Mayo Clinic
Address: Division of Biostatistics - Harwick 7, Rochester, MN, 55905, United States
Keywords: variance components ; threshold model ; non-normality ; box-cox transformation
Abstract:

Variance components approach is one of the most used methods in quantitative genetics analysis. This approach is based on the assumption that the trait distributions are normal. When the distributions are not normal, several transformation approaches have been proposed. In this paper, we will compare different transformations and their impact in the heritabilities and genetic correlations using real and simulated data.

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