JSM 2005 - Toronto

Abstract #304198

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 191
Type: Contributed
Date/Time: Monday, August 8, 2005 : 2:00 PM to 3:50 PM
Sponsor: General Methodology
Abstract - #304198
Title: The Role of Viral Load Measures in the Cost-effectiveness Analysis of ART
Author(s): Martha Lee*+ and Juwon Song
Companies: Georgetown University and The University of Texas Health Science Center at Houston
Address: 1021 Arlington Blvd Apt 731, Arlington, VA, 22209, United States
Keywords: Economic evaluation ; cost-effectiveness analysis ; Antiretroviral therapy ; HIV/AIDS ; viral load ; mathematical modeling
Abstract:

The cost-effectiveness of combination antiretroviral therapy for HIV-infected patients has been evaluated in the developed and developing countries. Viral load testing has been considered a key cost driver for delivering ART. WHO recognized that viral load testing may not be feasible in many developing countries. Therefore, viral load tests have been omitted in patients receiving ART. In standard methods of cost-effectiveness analysis---outcome measure, for instance---the Quality Adjusted Life Year (QALY) gained has been used frequently. This study is to investigate costs of viral load testing in different settings, the optimal frequency of viral load tests during the course of ART delivery, using mathematical models to estimate the number of HIV infections averted by ART based on the information of viral load measurements, and assessing the cost-effectiveness of ART with viral load measures.

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Revised March 2005