JSM 2005 Online Program

Abstract #304004

This is the preliminary program for the 2005 Joint Statistical Meetings in Minneapolis, Minnesota. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2005); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

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Activity Number:	99
Type:	Contributed
Date/Time:	Monday, August 8, 2005 : 8:30 AM to 10:20 AM
Sponsor:	Biometrics Section
Abstract - #304004
Title:	Confidence Intervals for the Ratio of Two Proportions: A Review and Evaluation of Methods
Author(s):	James Lymp*+ and Ross A. Dierkhising
Companies:	Child Health Institute and Mayo Clinic
Address:	6200 NE 74th St, Seattle, WA, 98115-8160, United States
Keywords:
Abstract:	The ratio of two proportions is widely used, for example to estimate relative risk in epidemiology and the likelihood ratio of a diagnostic test. Yet even though this estimate is derived using only four values from a 2 by 2 contingency table, there are at least 12 known methods to estimate confidence intervals. We review these methods, providing heuristic justification for each and a common terminology for easy comparison. We illustrate similarities and differences between methods using data from a study of computerized decision support for pediatric care. We evaluate coverage properties of each method in a variety of scenarios. Confidence intervals and coverage differ substantially between methods when the sample size is small or when either proportion is near 0 or 1. We provide guidance on choice of method for a selection of common scenarios.

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