JSM 2005 Online Program

Abstract #303996

This is the preliminary program for the 2005 Joint Statistical Meetings in Minneapolis, Minnesota. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2005); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

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Activity Number:	74
Type:	Contributed
Date/Time:	Sunday, August 7, 2005 : 8:00 PM to 9:50 PM
Sponsor:	Section on Statistics in Epidemiology
Abstract - #303996
Title:	Clinical vs. Statistical View of the Association of Waist vs. Body Mass Index with Incident Diabetes: A Literature-based Metaanalysis
Author(s):	Gabriela Vazquez*+ and Sue Duval and David Jacobs
Companies:	University of Minnesota and University of Minnesota and University of Minnesota
Address:	1300 S Second street Suite 300, Minneapolis, MN, 55454, United States
Keywords:	meta-analysis ; diabetes ; obesity
Abstract:	This paper attempts to compare the magnitude of association between total and visceral obesity indicators with diabetes incidence. Body mass index (BMI), waist circumference (WC), and waist to hip ratio (WHR) have been shown to be associated with diabetes in cross-sectional and prospective studies. From the clinical perspective, visceral adiposity (approximated by WC or WHR) is preferred to total adiposity (BMI), as it is known to generate diabetogenic substances. However, from the statistical perspective, BMI and WC are unlikely to yield different answers because of their high correlation. A metaanalysis was conducted for published studies that included information on the association of incident diabetes with BMI, WC, and WHR. The analysis was performed with 32 studies from 432 publications initially retrieved from a PubMed search. Measures of association were transformed to a RR per 1 SD increase in the obesity indicator. Random-effects models were used to compute pooled estimates.

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