JSM 2005 - Toronto

Abstract #303358

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Activity Number: 474
Type: Topic Contributed
Date/Time: Thursday, August 11, 2005 : 8:30 AM to 10:20 AM
Sponsor: Section on Bayesian Statistical Science
Abstract - #303358
Title: Reconstructing Posterior Distributions of a Species Phylogeny Using Estimated Gene Tree Distributions
Author(s): Liang Liu*+ and Dennis Pearl
Companies: The Ohio State University and The Ohio State University
Address: 693 Trumbull Court, Columbus, OH, 43210, United States
Keywords: species tree ; gene tree ; coalescence
Abstract:

In this paper, we propose a Bayesian method to estimate the phylogenetic tree of a group of species using multiple estimated gene tree distributions such as those in a Bayesian analysis of DNA sequence data. The whole process can be represented as a two-step Markov chain, from species tree to gene tree and from gene tree to DNA sequences. The first step can be explained by coalescent theory. The process of the second step follows an evolutionary model at the molecular level. A two-step Markov chain Monte Carlo method is used to generate the set of species trees from its posterior distribution. The method is applied to analyze both simulated and experimental DNA sequence data.

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