JSM 2005 Online Program

Abstract #302560

This is the preliminary program for the 2005 Joint Statistical Meetings in Minneapolis, Minnesota. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2005); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

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Activity Number:	300
Type:	Invited
Date/Time:	Tuesday, August 9, 2005 : 2:00 PM to 3:50 PM
Sponsor:	Section on Statistics in Epidemiology
Abstract - #302560
Title:	Strata-Matched Case Control Study or Just a Stratified Analysis: The Confusion of Naming
Author(s):	Madhu Mazumdar*+
Companies:	Weill Medical College of Cornell University
Address:	411 E. 69th. Street, KB-323, New York, NY, 10021,
Keywords:	Strata-Matched Case Control Study ; Risk set Sampling
Abstract:	Randomized trials are becoming increasingly difficult to complete due to the low accrual issues. Randomized trials with surgery versus chemotherapy plus surgery have always been harder because of patients' eagerness to get the surgery right away, rather than prolonging the time to surgery by having chemotherapy first. Chemotherapy in adjuvant setting also is hard to promote because administering therapy when the disease is absent is not a popular concept. Patients prefer to keep the decision in their hands rather than on the flip of a coin. However, many patients do receive chemotherapy in neoadjuvant and adjuvant setting, and their data gets captured in the consecutive patients' database more than many surgical groups routinely collect. Clinicians often utilize these databases to assess the effect of chemotherapy by performing retrospective comparative studies. This paper assesses if there is any gain in utilizing sampling strategies at this stage over approaching this issue with proper analyses and modeling.

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