JSM 2005 - Toronto

Abstract #304391

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 362
Type: Contributed
Date/Time: Wednesday, August 10, 2005 : 8:30 AM to 10:20 AM
Sponsor: Section on Nonparametric Statistics
Abstract - #304391
Title: Nonparametric Estimation for Competing-risk, Current-status Data: Convex Minorant Characterizations and Algorithms
Author(s): Marloes Maathuis*+
Companies: University of Washington
Address: University of Washington, Seattle, WA, 98195-4322, United States
Keywords: current status ; competing risk ; maximum likelihood
Abstract:

We study nonparametric estimation of the subdistribution functions for competing-risk, current-status data. In particular, we consider the nonparametric maximum likelihood estimator (MLE) and the "naive estimator" proposed by Jewell, Van der Laan, and Henneman (2003). We present a new characterization for the MLE and use it to derive several self-induced convex minorant characterizations. These characterizations provide insight into the relationship between the MLE and the naive estimator and lead to iterative convex minorant algorithms for the computation of the MLE. We discuss one such algorithm in detail and prove its convergence. Finally, we compare the MLE and several variants of the naive estimator in a simulation study and show that the MLE is superior to the naive estimators in terms of mean-squared error.


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