JSM 2005 - Toronto

Abstract #303576

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 124
Type: Topic Contributed
Date/Time: Monday, August 8, 2005 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #303576
Title: Responder Analysis: You Can Have It Both Ways
Author(s): Thomas Permutt and Joan Buenconsejo*+
Companies: U.S. Food and Drug Administration and U.S. Food and Drug Administration
Address: 5600 Fishers Ln (HFD-715), Rockville, MD, 20857,
Keywords: empirical CDF
Abstract:

Dichotomous outcomes offer easy interpretability (success or failure) and, sometimes, the least bad approach to dropouts (count them as failures). Information is lost, however, when continuous outcomes are reduced to dichotomies. It is a false choice, nevertheless, between continuous methods and binary methods. Rank methods can have the advantages of both: the interpretability of dichotomous methods and the efficiency of continuous methods.

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Revised March 2005