JSM 2005 - Toronto

Abstract #302690

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Legend: = Applied Session, = Theme Session, = Presenter
Activity Number: 505
Type: Invited
Date/Time: Thursday, August 11, 2005 : 10:30 AM to 12:20 PM
Sponsor: Section on Health Policy Statistics
Abstract - #302690
Title: Do You Believe in RCTs or Observational Studies?
Author(s): Suna Barlas*+
Companies: Merck & Co., Inc.
Address: BL32, Bluebell, PA, 19422,
Keywords: observational study ; randomized clinical trials
Abstract:

This talk will evaluate the often asked question "Should we believe in randomized clinical trials or observational studies?" We believe this is not a fair question as these two groups of studies answer different questions and one is more desirable under certain circumstances. The question should be "Do we believe in good science?" There certainly are poorly designed observational studies, and often data arising from these studies are poorly analyzed. However that does not indicate by any means that observational studies are not suitable to answer a set of scientific questions. By the same token, there certainly are badly designed clinical trials whose results cannot be generalized, mostly due to inclusion/exclusion criteria, dropouts, and other design-related issues.

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Revised March 2005