JSM 2004 - Toronto

Abstract #301941

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Activity Number: 427
Type: Contributed
Date/Time: Thursday, August 12, 2004 : 10:30 AM to 12:20 PM
Sponsor: General Methodology
Abstract - #301941
Title: A Generalized Estimating Equations Approach to Analyzing a Replicated cDNA Microarray Experiment
Author(s): Susan J. Simmons*+ and Meng Wu and Ann Stapleton
Companies: University of North Carolina, Wilmington and University of North Carolina, Wilmington and University of North Carolina, Wilmington
Address: , Wilmington, NC, 28403,
Keywords: generalized estimating equations ; microarray
Abstract:

We investigate the use of a GEE model in a cDNA microarray experiment that contains, on average, three replicated spots per gene on each array. The microarrays are created from two different lines of maize with information regarding UV treatment versus control on each array. This methodology allows us to look at possible differences in gene expression involved in the interaction of treatment and line, as well as by treatment alone and line alone.


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