JSM 2004 - Toronto

Abstract #301908

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Activity Number: 200
Type: Contributed
Date/Time: Tuesday, August 10, 2004 : 9:00 AM to 10:50 AM
Sponsor: Section on Statistics in Epidemiology
Abstract - #301908
Title: Techniques for fMRI Visual Field Diagram Analysis
Author(s): Raymond G. Hoffmann*+
Companies: Medical College of Wisconsin
Address: PO Box 26509, Milwaukee, WI, 53226,
Keywords: fMRI ; spatial statistics ; areal models ; geostatistical models
Abstract:

A visual field diagram is a 2D projection of the regions of the brain activated by a visual stimulus. The projection is a time-dependent areal map of the activation levels of the voxels obtained from an fMRI scan. The projection is in a circular region corresponding to the visual field usually used for assessing retina sensitivity. Analysis of the visual field diagram has usually resulted from dividing the circle into 24 radial regions of pi/4 radians and three concentric rings about the center of the diagram. Statistical analysis, at best, has resulted in treating these 24 regions as a 24-point repeated measures analysis without any spatial structure. The current study uses simulated data with known effect structure and actual fMRI spatial correlation to compare the effectiveness of (1) a linear repeated measures with no assumed structure, (2) a two-factor repeated measures with eight angles and three distances from the origin, (3) an areal spatial model for the 24 segments, and (4) a geostatistical model for the over 663 projected voxels.

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