JSM 2004 - Toronto

Abstract #300516

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Activity Number: 424
Type: Contributed
Date/Time: Thursday, August 12, 2004 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #300516
Title: The Relationship of the 6-minute Test to Maximal Oxygen Consumption under Skew-normal Assumptions
Author(s): Corrado Crocetta*+ and Nicola Loperfido
Companies: Università di Foggia and Università di Urbino
Address: Via IV Novembre, 1, Foggia, International, 71100, Italy
Keywords: 6-min. walk test ; maximal oxygen consumption ; skew-normal distribution ; cardiopulmonary exercise testing
Abstract:

Many authors showed that Peak Oxygen Uptake (Vo2 max) is the best predictor of long-term overall and event-free survival in patient with advanced heart failure. The Vo2 max is quite expensive and sometimes it cannot even be performed. Lipkin et al. (1988) found a curvilinear relationship between distances abulated during the Six Minutes Walk Test (6-WT) and Vo2 max. Some authors used linear regression to predict Vo2 max from the results of 6-WT, under the normality assumption. We show that the assumption of normality can be misleading and that a skew-normal distribution is more appropriate when predicting Vo2 max using 6-WT.

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