JSM 2004 Online Program

Abstract #300202

This is the preliminary program for the 2004 Joint Statistical Meetings in Toronto, Canada. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2004); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

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Activity Number:	205
Type:	Invited
Date/Time:	Tuesday, August 10, 2004 : 10:30 AM to 12:20 PM
Sponsor:	Section on Physical and Engineering Sciences
Abstract - #300202
Title:	Statistical Considerations for 96-well Plates
Author(s):	Douglas Hawkins*+
Companies:	University of Minnesota
Address:	School of Statistics, Minneapolis, MN, 55455,
Keywords:	spatial effects ; clinical chemistry
Abstract:	The 8x12 96-well plate has long been the workhorse for clinical chemistry assays. Now it, and larger variants, are playing a vital role in high throughput screening and factorial experiments. There can be substantial location effects in the different wells of the plate. Traditional layouts in which for example calibrators and controls always go into the same plate location confound these location effects with treatment differences. Methods from agricultural experimentation where similar (though generally nonsystematic) effects occur can be used profitably in a more thoughtful allocation to the wells.

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