JSM 2004 - Toronto

Abstract #302164

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Activity Number: 343
Type: Contributed
Date/Time: Wednesday, August 11, 2004 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #302164
Title: A Study of Deaths Due to Cardiovascular Diseases through Markovian Multistate Models
Author(s): Somesh Chattopadhyay*+ and Daniel McGee
Companies: Florida State University and Florida State University
Address: Dept. of Statistics, Tallahassee, FL, 32306-4330,
Keywords: multistate models ; Markov models ; multivariate survival analysis ; cardiovascular disease ; competing risks ; recurrent events
Abstract:

In the survival analysis of cardiovascular diseases the reason for death may be one or more reasons. Also there are different states of a patient from which the patient can move only to a few other states. Some of the conditions of the patient can lead to other conditions. Some of the conditions of the patient may recur as well. In this situation, times to different events are correlated. It is important to investigate the relationship of different causes for death and different events and their joint impact on the patient. In this set-up, a multistate model may be the most appropriate to study the relationship between different cardiovascular events and death. We propose a Markovian multistate model which also retains some past history of cardiovascular disease events of the patient. We investigate the relationship of different causes of death through this kind of model using the data from Framingham study.


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