JSM 2004 - Toronto

Abstract #302119

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Activity Number: 437
Type: Contributed
Date/Time: Thursday, August 12, 2004 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #302119
Title: Which P Value is Correct? An Application of Randomization Test Procedure in a Lung Transplant Trial
Author(s): Yulan Li*+
Companies: Novartis Pharmaceuticals
Address: One Health Plaza, East Hanover, NJ, 07936,
Keywords: parametric test ; randomization test ; permutation ; exact p value
Abstract:

Generally, in inferential statistical data analyses, p values are obtained using the parametric tests assuming the test statistics follow certain parametric distributions. However, this assumption is not always relaiable, that is, p values obtained based on the assumption could be very different from those obtained using the randomization test procedures. Thus, investigation of parametric test procedures can be crucial to the conclusions. Permutation and design-based randomization test procedures are assessed to determine the correct p value. A real example in transplant trial was used for illustration.


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