JSM 2004 - Toronto

Abstract #301729

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Activity Number: 104
Type: Topic Contributed
Date/Time: Monday, August 9, 2004 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #301729
Title: Maximum Likelihood Inference of Species Trees under the Coalescent Process
Author(s): James H. Degnan*+
Companies: University of New Mexico
Address: Dept. of Mathematics and Statistics, Albuquerque, NM, 87131,
Keywords: phylogeny ; gene tree ; coalescence ; maximum likelihood
Abstract:

An evolutionary tree, or phylogeny, which reflects the evolutionary history of a set of species, might differ from the trees that reflect the evolutionary history of the genes from the same set of species. A tree reflecting the history of the species is called a species tree; a tree relfecting the history of a gene is called a gene tree. The goal of this talk is to implement maximum likelihood inference of the species tree from a set of (known) gene trees, assuming the coalescent process. This requires having both the likelihood of the gene tree and the probability of the gene tree given the species tree. Although methods for computing the likelihood of gene trees have been available for many years, until recently the probability of a gene tree for a given species tree has only been worked out for small trees--five or fewer species. This talk includes a method for computing this probability for an arbitrary number of species and the application of this method to the maximum likelihood inference of species trees.

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