JSM 2004 Online Program

Abstract #301686

This is the preliminary program for the 2004 Joint Statistical Meetings in Toronto, Canada. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2004); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

To View the Program:
You may choose to view all activities of the program or just parts of it at any one time. All activities are arranged by date and time.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.

Back to main JSM 2004 Program page

Activity Number:	310
Type:	Contributed
Date/Time:	Wednesday, August 11, 2004 : 8:30 AM to 10:20 AM
Sponsor:	Biometrics Section
Abstract - #301686
Title:	Testing for Homogeneity in Genetic Linkage Analysis
Author(s):	Yuejiao Fu*+ and Jiahua Chen and Jack Kalbfleisch
Companies:	University of Waterloo and University of Waterloo and University of Michigan
Address:	Dept. of Statistics and Actuarial Science, Waterloo, ON, N2L 3G1, Canada
Keywords:	genetic linkage analysis ; hypothesis testing ; local asymptotic power ; mixture models ; modified likelihood ; recombinant
Abstract:	We apply the modified likelihood ratio test to two binomial mixture models arising in genetic linkage analysis. The limiting distribution of the test statistic for both models is shown to be a mixture of chi-squared distributions. A consideration of random family sizes for both models gives similar results. We also explore the power properties under local alternatives. Simulation studies show that the modified likelihood ratio test is more powerful than other methods under a variety of model specifications.

The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2004 program