JSM 2004 Online Program

Abstract #300934

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Activity Number:	112
Type:	Contributed
Date/Time:	Monday, August 9, 2004 : 10:30 AM to 12:20 PM
Sponsor:	Biopharmaceutical Section
Abstract - #300934
Title:	A New Testing Approach for Comparing the Overall Homogeneity of Survival Curves
Author(s):	Hongkun Wang*+ and Xun Lin
Companies:	University of Rochester and Pfizer Global Research and Development
Address:	60 Crittenden Blvd. Apt. 732, Rochester, NY, 14620,
Keywords:	survival analysis ; censoring ; log-rank test ; Wilcoxon test ; statistical power
Abstract:	A new statistical testing approach is developed for comparing the overall homogeneity of survival curves. The proposed new method has greater power than the commonly used tests to detect overall differences between crossing survival curves. The small-sample performance of the new test is investigated under a variety of situations by means of Monte Carlo simulations. Furthermore, the applicability of the proposed testing approach is illustrated by a real data example from a kidney dialysis trial.

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