JSM 2004 - Toronto

Abstract #300689

This is the preliminary program for the 2004 Joint Statistical Meetings in Toronto, Canada. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 7-10, 2004); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

To View the Program:
You may choose to view all activities of the program or just parts of it at any one time. All activities are arranged by date and time.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.

Back to main JSM 2004 Program page
Activity Number: 405
Type: Contributed
Date/Time: Thursday, August 12, 2004 : 8:30 AM to 10:20 AM
Sponsor: Biopharmaceutical Section
Abstract - #300689
Title: Stochastic Models for Compliance Analysis and Applications
Author(s): Junfeng Sun*+ and Haikady N. Nagaraja
Companies: Ohio State University and Ohio State University
Address: 650 Trumbull Ct., Columbus, OH, 43210,
Keywords: electronic event-monitoring ; compliance ; stochastic modeling ; Markov-dependent mixture models ; empirical Bayes
Abstract:

Compliance is the extent to which a patient follows the prescribed regimen. It is crucial to accurately measure compliance in both clinical trials and medical practice. It has received a lot of attention in the medical literature. However, little effort has been made to study the statistical properties of various compliance metrics. This study utilizes the information-rich electronic event monitoring (EEM) data and studies the statistical properties of several clinically meaningful compliance metrics. Markov-dependent mixture models are applied for the metrics based on continuous data. To pool the data from different patients, we use empirical Bayes approaches. As an illustration, we apply these metrics to an AIDS clinical trial. Practical applications of these compliance metrics will also be discussed.

  • The address information is for the authors that have a + after their name.
  • Authors who are presenting talks have a * after their name.

Back to the full JSM 2004 program

JSM 2004 For information, contact jsm@amstat.org or phone (888) 231-3473. If you have questions about the Continuing Education program, please contact the Education Department.
Revised March 2004