JSM 2004 Online Program

Abstract #300398

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Activity Number:	109
Type:	Topic Contributed
Date/Time:	Monday, August 9, 2004 : 10:30 AM to 12:20 PM
Sponsor:	Section on Health Policy Statistics
Abstract - #300398
Title:	Statistical Cost-effectiveness Analysis: Incremental Net Benefit
Author(s):	Andrew R. Willan*+
Companies:	Research Institute, HSC
Address:	Population Health Sciences, Toronto, ON, M5G 1X8, Canada
Keywords:	clinical trials ; cost-effectiveness ; incremental net benefit
Abstract:	The collection of patient level cost data in clinical trials initially led investigators to conduct statistical inference on the incremental cost-effectiveness ratio (ICER). The problems with ratio statistics, however, quickly led to the proposal for using the incremental net benefit (INB) as an alternative. We illustrate how INB solves the each of the problems associated with ICERs. A brief discussion on censored data and covariate adjustment will also be given.

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