Abstract #302051

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JSM 2003 Abstract #302051
Activity Number: 227
Type: Invited
Date/Time: Tuesday, August 5, 2003 : 10:30 AM to 12:20 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #302051
Title: Replication, Experimental Design, and Models for the Analysis of Two-Color Microarray Data
Author(s): Kathleen Kerr*+
Companies: University of Washington
Address: Biostatistics, Seattle, WA, 98195-7232,
Keywords:
Abstract:

Two characteristics of microarray experiments are multiple sources of systematic variation and multiple sources of error. This talk considers the consequences of these characteristics on experimental design for two-color microarrays. The relative merits of different kinds of "replication" will be discussed. Different modeling frameworks appear in the literature for discussing experimental design for microarrays. I will discuss the basic equivalence of these frameworks and their consequences for experimental design.

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