Abstract #301829

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JSM 2003 Abstract #301829
Activity Number: 299
Type: Contributed
Date/Time: Tuesday, August 5, 2003 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #301829
Title: Statistical Analysis of Calibration Data Derived from the Analysis of MDMA and Related Compounds
Author(s): Wenyaw Chan*+ and Dung-Tsa Chen and Seng-Jaw Soong and Dong-Liang Lin and Ray Liu
Companies: University of Texas, Houston and University of Alabama, Birmingham and University of Alabama and Institute of Forensic and University of Alabama
Address: 1200 Herman Pressler, Suite 1015E, Houston, TX, 77225-0186,
Keywords: calibration ; jackknife method
Abstract:

Whether a single isotopic-analog is applicable to quantification of various drugs of abuse is of interest in forensic science. We present a dataset of MDMA (Methylenedioxymethamphetamine) and related compounds with several calibration runs. We search the possible functional forms of a calibration curve for MDMA by using various exploratory approaches. We also use a jackknife approach based on a single calibration run data (i.e., leave-one-in approach) to predict MDMA concentrations in the other run datasets. To evaluate prediction of MDMA concentrations by other isotopic-analogs, the reaction readings of each isotopic-analog is applied to those of MDMA. The prediction errors from the jackknife approach are used to test whether quantitative results derived from other isotopic-analogs are not different from those from the MDMA isotopic-analog.

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