Abstract #301659

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JSM 2003 Abstract #301659
Activity Number: 127
Type: Contributed
Date/Time: Monday, August 4, 2003 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #301659
Title: Estimating Incidence Rates Using Pedigree Sampling
Author(s): Amy K. Ferketich*+ and Steven N. MacEachern and Stanley A. Lemeshow and Judy Westman and Lei Shen and Albert De La Chapelle and Clara Bloomfield
Companies: The Ohio State University and Ohio State University and The Ohio State University and The Ohio State University and The Ohio State University and The Ohio State University and The Ohio State University
Address: 320 W 10th Ave., School of Public Health, Columbus, OH, 43210-1280,
Keywords:
Abstract:

Little is known about cancer incidence in the Amish.The Amish Population Cancer Study was conducted to determine the incidence and prevalence of cancers in the Amish, identify those at risk for developing cancer, and provide education on cancer. In this study, 92 households were sampled from a total of 4,512 in Holmes County, Ohio, during a six-month period in 2000. For each household sampled, a complete cancer family history was taken from the proband and the proband's spouse. In some households this "list" of family members contained several hundred individuals. This sampling procedure led to data on 26,679 individuals who were alive during the reference period, 1996-1999. Many people appeared on several household lists, due to the Amish family structure. A total of 108 adult and 3 childhood cancer cases were reported between 1996 and 1999. Here, we describe how we estimated the 4-year cancer incidence rates. We will present the results of the simulation studies conducted to study the properties of the various methods considered and provide suggestions on how to improve the sampling design to obtain data on cancer incidence among small closed populations.

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