Abstract #301396

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JSM 2003 Abstract #301396
Activity Number: 187
Type: Invited
Date/Time: Tuesday, August 5, 2003 : 8:30 AM to 10:20 AM
Sponsor: WNAR
Abstract - #301396
Title: What Can Death Tell Us About Functional Decline in Aging?
Author(s): Laurel A. Beckett*+
Companies:
Address: 2600 Kline Ct., Davis, CA, 95616-7668,
Keywords: survival aging ; missing data ; longitudinal data
Abstract:

One of the most widely noted and feared phenomena of aging is functional decline, whether in cognition, mobility or strength. Longitudinal studies offer us a chance to characterize the variety of paths people follow as they age, and to try to fIgure out why some people decline very rapidly and others retain function. In logitudidal studies of aging, we lose many participants to death. Statisticians forcusing on longitudinal change often treat death as an annoying and inconvenient cause of censoring. But we also could view death as offering useful information, both through its timing and through the availability of post-mortem data that cannot be obtained during life. I will talk about ways we can use information arising from death of participants in longitudinal studies in the context of Alzheimer's disease research, and illustrate with examples from the Religious Orders Study.

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Revised March 2003