Abstract #300150

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JSM 2003 Abstract #300150
Activity Number: 460
Type: Invited
Date/Time: Thursday, August 7, 2003 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #300150
Title: Robust M-Estimation Methods in Clinical Trials
Author(s): Dennis Boos*+
Companies: North Carolina State University
Address: Department of Statistics, Raleigh, NC, 27695-8203,
Keywords: M-estimation ; Wald test ; score test ; likelihood ratio test
Abstract:

This talk will give a brief overview of M-estimation methods that are appropriate for ANOVA and regression models with clinical trial data. This includes generalized Wald, score, and likelihood ratio tests and confidence intervals. The advantage of these methods over least squares is similar to that of the Wilcoxon rank sum test compared to the t test.

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