Abstract #300098

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JSM 2003 Abstract #300098
Activity Number: 127
Type: Contributed
Date/Time: Monday, August 4, 2003 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #300098
Title: Balancing Population Size and Genetic Information in Parentage Analysis Studies
Author(s): Beatrix Jones*+
Companies: SAMSI
Address: PO Box 14006, Research Triangle Pk, NC, 27709-4006,
Keywords: parentage analysis ; genetics ; mating ; fertility ; dispersal ; study design
Abstract:

In parentage analysis studies, the parameters of interest typically are not the parent assignments themselves, but population parameters such as variance in fertility, self-pollination rate, or average dispersal distances. The precision of parameter estimates is affected by two factors: the number of offspring under consideration and the precision with which the offspring can be assigned to parents. When assignment of parents is based on genetic information, the confidence in assignments is affected by the number and polymorphism of the loci considered, and by the number of potential parents in the population. Studying larger populations may yield higher numbers of offspring, but since larger populations contain more potential parents, more (or more highly polymorphic) loci are necessary to attain a given level of confidence in the parent assignments. This paper addresses how to balance the size of the population and the number of loci when designing a study. It is shown that the number of loci needed to assign all offspring unambiguously is proportional to the logarithm of the population size.

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