Abstract #301741

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JSM 2003 Abstract #301741
Activity Number: 259
Type: Luncheons
Date/Time: Tuesday, August 5, 2003 : 12:30 PM to 1:50 PM
Sponsor: Section on Health Policy Statistics
Abstract - #301741
Title: Health Economics Analyses and Modeling for Clinical Trials in Drug Development
Author(s): Christopher M. Barker*+
Companies: MEDTAP International Inc.
Address: 303 Twin Dolphin Drive, Redwood City, CA, 94065-1497,
Keywords: health economics ; outcomes research ; modeling
Abstract:

Health economics analyses have become an indispensable component of the drug development process. Their main objective is to estimate cost effectiveness. Statistical issues for these analyses range from estimation of confidence intervals to more recent application of Bayesian methods. Developing a model may involve estimating outcomes that were not necessarily collected in the randomized clinical trial itself. Examples include modeling and extrapolating survival beyond the study period of the clinical trials, or estimating quality adjusted life years, or "QTWIST." The measurement of utilities and the use of statistical methods such as conjoint analysis are less well known to practicing clinical trial statisticians. Participants in the roundtable are invited to share their experiences in planning and conducting health economics analyses. Participants in the roundtable are invited to share their experiences in planning and conducting health economics analyses.

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Revised March 2003