Abstract #301598

This is the preliminary program for the 2003 Joint Statistical Meetings in San Francisco, California. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 2-5, 2003); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

To View the Program:
You may choose to view all activities of the program or just parts of it at any one time. All activities are arranged by date and time.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.

Back to main JSM 2003 Program page
JSM 2003 Abstract #301598
Activity Number: 421
Type: Contributed
Date/Time: Wednesday, August 6, 2003 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #301598
Title: Causal Effects in Randomized Trials in the Presence of Partial Compliance
Author(s): Tong Guo*+ and Robert W. Platt
Companies: Montreal Childrens Hospital and McGill University
Address: 25 Broad St. Ext., Groton, CT, 06340-3745,
Keywords: partial compliance ; intention-to-treat analysis ; complier average causal effect ; Rubin causal model ; breastfeeding promotion intervention
Abstract:

The noncompliance problem in randomized clinical trials is at the heart of the intention-to-treat (ITT) framework and is attracting substantial attention recently. However, the focus is limited to dichotomous classification of compliance behavior, which is often not the case in reality. We extend the description of compliance behavior from all-or-none treatment compliance defined by Imbens and Rubin (1997) to a trichotomous classification of full-partial-none compliance. In addition to complier average causal effect), we define none-to-partial-complier average causal effect and partial-to-full-complier average causal effect based on the framework of the Rubin causal model. Our discussion focuses on randomized trials with a binary treatment assignment. We apply our new methodology to a breastfeeding promotion intervention trial to evaluate the impact of full and partial breastfeeding on infant infectious outcomes.

  • The address information is for the authors that have a + after their name.
  • Authors who are presenting talks have a * after their name.

Back to the full JSM 2003 program

JSM 2003 For information, contact meetings@amstat.org or phone (703) 684-1221. If you have questions about the Continuing Education program, please contact the Education Department.
Revised March 2003