JSM 2003 Online Program

Abstract #301083

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Activity Number:	421
Type:	Contributed
Date/Time:	Wednesday, August 6, 2003 : 2:00 PM to 3:50 PM
Sponsor:	Biopharmaceutical Section
Abstract - #301083
Title:	Statistical Processing of Telemetric Food Intake Data for Preclinical Obesity Studies
Author(s):	Donghui Zhang*+
Companies:	Merck & Co., Inc.
Address:	Box 2000, RY84-16, Rahway, NJ, 07065,
Keywords:	obesity study ; food intake data ; automated data acquisition ; robust smoothing
Abstract:	In lab animal studies for obesity research, various automated multichannel data acquisition systems have been used to monitor food consumption of groups of animals continuously over a period of time. Such recorded food weight data usually have large volumes and are associated with various artifacts. We have developed a simple three-step robust smoothing algorithm that can effectively smooth various artifacts in food weight data, and we have implemented a highly automated statistical software tool to smooth and to summarize data in formats suitable for further statistical analysis.

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