JSM 2003 Online Program

Abstract #300946

This is the preliminary program for the 2003 Joint Statistical Meetings in San Francisco, California. Currently included in this program is the "technical" program, schedule of invited, topic contributed, regular contributed and poster sessions; Continuing Education courses (August 2-5, 2003); and Committee and Business Meetings. This on-line program will be updated frequently to reflect the most current revisions.

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Activity Number:	425
Type:	Contributed
Date/Time:	Wednesday, August 6, 2003 : 2:00 PM to 3:50 PM
Sponsor:	Biopharmaceutical Section
Abstract - #300946
Title:	Evaluation of Arthritic Progression Ordinal Data
Author(s):	Vasilis Bill Pikounis*+
Companies:	Merck Research Laboratories
Address:	PO Box 2000 RY84-16, Rahway, NJ, 07065-4607,
Keywords:	collagen ; proportional odds ; multinomial ; odds ratio ; repeated measures
Abstract:	The injection of collagen into mice induces the onset of arthritis in their paws. This assay is used to determine the efficacy of compounds that can slow the progression of the arthritis. The severity of the arthritis is measured on an ordinal scale from 0 to 5 across the time course of the study design. This presentation will summarize findings from the application of several approaches for modeling such growth curves, with an emphasis on the estimation and interpretation of effects.

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