Abstract #300755

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JSM 2003 Abstract #300755
Activity Number: 112
Type: Topic Contributed
Date/Time: Monday, August 4, 2003 : 10:30 AM to 12:20 PM
Sponsor: Section on Risk Analysis
Abstract - #300755
Title: Risk Analysis of the Public Health Impacts of Transmissible Spongiform Encephalopathies
Author(s): Steven A. Anderson*+
Companies: Food and Drug Administration
Address: CBER, Office of Biostatistics and Epidemiology, Rockville, MD, 20852-1428,
Keywords: public health ; tissue transplantation ; BSE ; Transmissible Spongiform Encephalopathies ; Monte Carlo ; CJD
Abstract:

Transmissible spongiform encephalopathies (TSEs) are a group of diseases that include bovine spongiform encephalopathy (BSE), a disease of cattle and the human; Variant Creutzfeldt Jakob Disease (vCJD); and classic Creutzfeldt Jakob Disease (CJD). These diseases pose a significant public health concern. In several instances CJD has been unknowingly transmitted during medical procedures such as cornea transplants and other tissue transplantation procedures. Also, there is a theoretical risk that these human diseases could be spread by blood products. We will demonstrate the application of probabilistic modeling in evaluating some of the public health risks posed by TSEs. The effectiveness of several possible risk reduction measures will also be explored using the model.

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