Abstract #300716

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JSM 2003 Abstract #300716
Activity Number: 180
Type: Contributed
Date/Time: Monday, August 4, 2003 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #300716
Title: Generalized Log-Rank Test for Interval-Censored Failure Time Data
Author(s): Qiang Zhao*+ and Jianguo (Tony) Sun
Companies: University of Missouri and University of Missouri
Address: Dept. of Statistics, Columbia, MO, 65211,
Keywords: follow-up studies ; nonparametric test ; failure time data analysis ; treatment comparison
Abstract:

This paper considers the problem of nonparametric treatment comparisons when only interval-censored failure time data are available, which often occurs in clinical trials and epidemiological studies. By interval-censored data, we mean that the survival time of interest is observed only to belong to an interval, instead of known or right-censored. For the problem, we generalize the most commonly used log-rank test for right-censored survival data. Numerical studies are conducted and reported to evaluate and compare the proposed test with the existing method, which indicate the presented method works well. We apply the method to a data set arising from an AIDS cohort study, which motivated the study.

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