Abstract #300662

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JSM 2003 Abstract #300662
Activity Number: 69
Type: Invited
Date/Time: Monday, August 4, 2003 : 8:30 AM to 10:20 AM
Sponsor: Section on Statistical Graphics
Abstract - #300662
Title: Visualization and Inference for Genomic Networks
Author(s): Vincent J. Carey*+
Companies: Channing Laboratory
Address: 181 Longwood Ave., Boston, MA, 02115-5804,
Keywords: bioinformatics ; graph structures ; visualization ; cancer genomics
Abstract:

Network structures are ubiquitous in genome biology. We will review methods of representing general network structures for exploratory data analysis and statistical modeling. Effective methods for exploring and testing hypotheses regarding gene expression, transcriptional regulation, and metabolic or disease processes require the integration of experimental and observational data, annotation resources, and tools for fitting and rendering models for graph structures. We will focus on methods developed in the Bioconductor initiative (www.bioconductor.org) with applications to genomics of cancer in humans.


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Revised March 2003