Abstract #300645

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JSM 2003 Abstract #300645
Activity Number: 413
Type: Contributed
Date/Time: Wednesday, August 6, 2003 : 2:00 PM to 3:50 PM
Sponsor: Section on Survey Research Methods
Abstract - #300645
Title: Comparing the Areas under Receiver Operating Characteristic Curves for Complex Survey Designs
Author(s): William W. Davis*+
Companies: National Institutes of Health
Address: 5114 Viking Rd., Bethesda, MD, 20814-5711,
Keywords: cluster sample ; mixed model ; jackknife ; balanced repeated replication
Abstract:

The receiver operating characteristic (ROC) curve may be used to evaluate the performance of a new diagnostic test relative to a standard diagnostic test. We provide a model-based approach to test whether the difference between two ROC curves is statistically significant when individuals are selected from a cluster sample design with unequal selection probabilities. The variance of the difference is expressed in terms of parameters of a mixed-model, which include parameters measuring the between- and within-cluster variation in both measurements. The model-based procedure offers an exact test under the model assumptions. The procedure is applied to detecting undiagnosed diabetes using data from the third National Health and Nutrition Examination Survey. For this example, the method is shown to yield similar conclusions to the approximate tests that utilize replication methods. Modeling the two diagnostic measurements yields insight that is not captured by the hypothesis test.


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