Abstract #300598

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JSM 2003 Abstract #300598
Activity Number: 67
Type: Invited
Date/Time: Monday, August 4, 2003 : 8:30 AM to 10:20 AM
Sponsor: Journal of Agricultural, Biological and Environmental Stats (JABES)
Abstract - #300598
Title: Gene Expression Data: The Technology and Statistical Analysis
Author(s): Bruce A. Craig*+ and Michael A. Black and Rebecca W. Doerge
Companies: Purdue University and Purdue University and Purdue University
Address: 1399 Mathematical Sciences, W. Lafayette, IN, 47907-1399,
Keywords: microarrays ; linear models ; hypothesis testing ; multiple comparisons ; statistical genetics
Abstract:

The desire to view the simultaneous behavior of genes affected by a stimulus at the total genome level has brought the scientific world to a new place in history. It is now commonplace to have an experiment that investigates the expression of thousands of genes across treatments and time points. We will discuss important aspects of the two most common microarray technologies, the spotted cDNA array and the oligonucleotide array, for the purpose of identifying common and unique features of each technology and the data produced. Two examples, each based upon one of the technologies, will be used for illustrative purposes in hopes of providing both encouragement and guidance to readers wanting to become more involved in this exciting field known as genomics.

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