Abstract #300570

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JSM 2003 Abstract #300570
Activity Number: 148
Type: Invited
Date/Time: Monday, August 4, 2003 : 2:00 PM to 3:50 PM
Sponsor: ENAR
Abstract - #300570
Title: Generalized Self-Consistency Methods for Cure Models
Author(s): Alexander Tsodikov*+
Companies: Huntsman Cancer Institute
Address: 2000 Circle of Hope Dr., Salt Lake City, UT, 84112-5550,
Keywords: semiparametric models ; cure models ; model building ; NPMLE
Abstract:

A unified approach is proposed for model building and construction of numerically efficient algorithms for maximum likelihood inference for a large class of semiparametric cure models. The approach is based on a generalization of the idea of self-consistency and links EM algorithms for frailty models and recently developed MM algorithms. Composition technique is developed for building hierarchical model families compatible with the algorithms.

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