Abstract #300344

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JSM 2003 Abstract #300344
Activity Number: 167
Type: Contributed
Date/Time: Monday, August 4, 2003 : 2:00 PM to 3:50 PM
Sponsor: Section on Health Policy Statistics
Abstract - #300344
Title: The Effect of Antidepressant Adherence on Diabetes Outcomes
Author(s): Kara Zivin Bambauer*+ and Stephen Soumerai and Connie Mah and Fang Zhang and Alyce S. Adams and Thomas J. McLaughlin
Companies: Harvard University Medical School and Harvard Medical School and Harvard Pilgrim Health Care and Harvard Pilgrim Health Care and Harvard University Medical School and Harvard University Medical School-Harvard Pilgrim Health Care
Address: 62 Donnybrook Rd. #1, Brighton, MA, 02135-1807,
Keywords: diabetes ; depression ; health outcomes ; generalized linear models ; mental health ; adherence
Abstract:

Depression often has a negative impact on diabetes health outcomes. Studies suggest that adherence to antidepressant medications (ADs) improves mental and physical health outcomes among depressed patients. How adherence to ADs affects diabetic outcomes has not been previously examined. Objective: To examine the relationship between adherence to ADs and glycemic levels among diabetic patients in a managed care setting. Methods: General linear models are used to estimate the effects of covariates including AD adherence on glycemic levels over time. Results: Adherence to ADs does not have a significant effect on glycemic levels among diabetic AD users. Younger age, number of comorbidities, diabetes severity, female gender, obesity, and nonwhite race have significant effects on glycemic levels. Conclusions: Although we observed no significant differences in glycemic levels among adherent and nonadherent AD users, our results confirm previously established associations between patient characteristics and glycemic control. Further research is needed to disentangle the complex relationship among depression, treatment adherence, and diabetes outcomes.

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