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Title
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* ! Use of Simulation in Clinical Trials and Statistical Inference
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Date / Time / Room
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Sponsor
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Type
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08/15/2002
10:30 AM -
12:20 PM
Room: H-Murray Hill Suite B
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Biometrics Section*, Biopharmaceutical Section*, ENAR, Section on Statistical Computing*
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Topic Contributed
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Organizer:
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Mani Y. Lakshminarayanan, Centocor, Inc
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Chair:
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Mani Y. Lakshminarayanan, Centocor, Inc
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Discussant:
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11:35 AM - Nalini Ravishanker, University of Connecticut
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Floor Discussion
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11:55 AM
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Description
Simulation is an integral part of statistical research, especially, as a tool to initially verify research hypotheses of problems that are mathematically intractable. It is an important tool, not just to generate data from an underlying distribution as in the case of classical statistics, but also to actually enumerate posterior distributions as in the case of Bayesian statistics. In this session, usefulness of simulations will be explored in statistical inference, and in biopharmaceutical drug portfolio management. As a part of statistical inference, complex trial designs will be considered with multiple treatment regimens in clinical trials setting. Illustrative examples will also be provided.
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