Abstract #301774


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JSM 2002 Abstract #301774
Activity Number: 39
Type: Contributed
Date/Time: Sunday, August 11, 2002 : 4:00 PM to 5:50 PM
Sponsor: Section on Statistics in Epidemiology*
Abstract - #301774
Title: Use of Independent Assumption in the "Matched" Study of Obstetrics and Gynecology
Author(s): Yen-Hong Kuo*+
Affiliation(s): Jersey Shore Medical Center, Meridian Health System
Address: 1945 State Route 33, Neptune, New Jersey, 07753, US
Keywords: matched study ; independent assumption ; case-control
Abstract:

This study was conducted to assess the use of independent assumption in the "matched" study. Articles published in the journals of "American Journal of Obstetrics and Gynecology" or "Obstetrics & Gynecology" in 2001 with the keyword of "matched" and clearly defined matching criteria in the abstract were identified via MEDLINE. A total of 23 articles with a case/treatment-to-control ratio of 1:1 were included. Among them, only 12 studies (52%) were actually 1-to-1 matched. The median number of matching criteria was three and the maximum was eight, when one self-controlled study was excluded. Age or gestational age was used as a criterion in ten studies (91%). For making comparisons, a total of three studies (25%) from both journals either used independent assumption (n=2) or did not specify (n=1). In all of the other eleven non 1-to-1 matched studies (either "matched" was used to indicate no statistically significant difference, or lacking of statements with respect to 1-to-1 matching), the independent assumption was used. This study reveals that the independent assumption was misused in some of the 1-to-1 matched studies. In addition, the inappropriate use of the term of "matched" was common.


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