Abstract #301309

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JSM 2002 Abstract #301309
Activity Number: 47
Type: Contributed
Date/Time: Sunday, August 11, 2002 : 4:00 PM to 5:50 PM
Sponsor: General Methodology
Abstract - #301309
Title: Cross-over Designs with Cost Constraints
Author(s): Sergei Leonov*+ and Valerii Fedorov and Byron Jones
Affiliation(s): GlaxoSmithKline, Inc. and GlaxoSmithKline, Inc. and GlaxoSmithKline, Inc.
Address: 1250 So Collegeville Rd, PO Box 5089, Collegeville, Pennsylvania, 19426-0989, USA
Keywords: cross-over design ; multiple responses ; cost constraints ; optimal design
Abstract:

We consider cross-over design models as multiresponse regression models where the covariance function may depend on unknown parameters. The use of convex design theory enables the introduction of cost constraints which makes the approach more applicable to practical situations. The optimality conditions and examples of optimal designs are provided.

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