Abstract #301259

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JSM 2002 Abstract #301259
Activity Number: 288
Type: Contributed
Date/Time: Wednesday, August 14, 2002 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section*
Abstract - #301259
Title: Model Misspecification Effects in Univariable Regression Models for Right-censored Survival Data
Author(s): Zdenek Valenta* and Chung-Chou Chang+ and Lisa Weissfeld
Affiliation(s): University of Pittsburgh and University of Pittsburgh and University of Pittsburgh
Address: E820 MUH, 200 Lothrop Street, Pittsburgh, Pennsylvania, 15213, USA
Keywords:
Abstract:

The study is performed to cross-analyze survival data which follows either a multiplicative or an additive model for the conditional hazard rate. We consider two different multiplicative models, Cox's proportional hazards model (1972) and Gray's time-varying coefficients model (1992). For the additive model, we use Aalen's (1980) linear model, which also incorporates time-varying coefficients. Particular attention is given to data exhibiting time-varying regression coefficients. The effect of misspecifying the true model on survival is assessed by looking at the power of the individual models to detect an existing effect, bias, and the mean square error.

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Revised March 2002