Abstract #301137


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JSM 2002 Abstract #301137
Activity Number: 252
Type: Contributed
Date/Time: Tuesday, August 13, 2002 : 2:00 PM to 3:50 PM
Sponsor: Section on Bayesian Stat. Sciences*
Abstract - #301137
Title: Bayesian Analysis of a Survival Model
Author(s): Subhashis Ghosal*+ and Sujit Ghosh
Affiliation(s): North Carolina State University and North Carolina State University
Address: 220 Patterson Hall, Box 8203, 2501 Founders Drive, Raleigh, North Carolina, 27695, U.S.A.
Keywords: survival analyis ; covariate ; censoring ; Dirichlet process ; mixture ; consistency
Abstract:

We consider a mixture of exponentials as a model for survival distribution in presence of a vector of covariates. Conditionally, on the value of a parameter $\lambda$, survival distributions are assumed to be independent exponential with parameters $\lambda\exp(-z_i'\beta)$. The unknown parameter $\lambda$ is assumed to follow a distribution $H$, which is completely unknown. Observations are assumed to be randomly right-censored. This model has an interesting property that the mean lifetime of observations, rather than the hazard rates, are directly related to the covariates. We do a Bayesian semiparametric analysis of the model by putting a Dirichlet prior on $H$. The posterior can be easily computed by MCMC algorithms. The resulting posterior is consistent under certain conditions.


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