Abstract #300569


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JSM 2002 Abstract #300569
Activity Number: 110
Type: Contributed
Date/Time: Monday, August 12, 2002 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section*
Abstract - #300569
Title: Analysis of Cross Sectional Cluster Ranomized Designs With the Logistic-Normal Likelihood Ratio Test
Author(s): Rafael Diaz*+
Affiliation(s): Tulane University
Address: 2114 Burdette Street, New Orleans, Lousiana, 70118, USA
Keywords: Groups of proportions ; logistic-normal ; test ; population average ; cluster-specific
Abstract:

The Logistic-normal likelihood ratio test has been proposed among the parametric techniques to compare two groups of proportions. However, it may be difficult to interpret intervention effects when using this test for cross-sectional cluster-randomized trials. This difficulty is due to the fact that the estimates in the Logistic-normal likelihood ratio test represent cluster-specific effects as opposed to population-average effects. The ready availability of software where this test has been implemented, and the optimal statistical properties of parametric techniques when the sample sizes are large enough, are two reasons to examine the usefulness of this cluster-specific technique for cross-sectional cluster randomized trials. This study examines two features of this test for this type of trial: its bias in estimating an intervention effect, and its power to detect one through Monte Carlo simulations for effect-sizes of interest.


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