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Title
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Room
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Statistics in Functional Genomics
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H-Roosevelt
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Date / Time
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Sponsor
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Type
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08/07/2001
10:30 AM
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12:20 PM
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ENAR
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Invited
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Organizer:
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Mark Yang, University of Florida
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Chair:
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Rebecca Doerge, Purdue University
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Discussant:
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Floor Discussion
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12:15 PM
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Description
The human genome project which tries to lay down the human 3 billion genetic codes, will soon be finished. The study of the codes themselves, called structural genomics, do not give the whole story of how the genes work together. The next hot research topic in genetics is to find out the order of the genes being used, or the functional genomics. One of the most promising tools in functional genomics is the microarray experiment which checks genes that are converted to mRNA in the cell at a given moment. When a tissue is observed over time, we may have an idea how many genes are acting together and in what order. Moreover, it can be used to classify the function of a tissue in cancer screening and disease diagnosis. However, microarray is subject to many sources of variation; from the between subject and within subject variations in sampling to the diffusion and hybridization variation in biochemical processing. Since this will be one of the hottest topics in genetics, we feel that statisticians might be interested in its current status of research and attend this session.
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