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Title
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Room
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Recent Statistical Developments in Evolutionary Genetics
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H-Gwinnett
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Date / Time
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Sponsor
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Type
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08/06/2001
8:30 AM
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10:20 AM
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ENAR
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Invited
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Organizer:
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Dennis Pearl, Ohio State University
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Chair:
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Hani Doss, Ohio State University
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Discussant:
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9:45 AM - Dennis Pearl, Ohio State University
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Floor Discussion
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10:15 AM
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Description
The advent of rapid nucleotide sequencing technology has unlocked many new areas of biological investigation, and also produced a variety of new data structures for which statistical methods based on independent observations of real-valued data do not apply. For example, the phylogenetic tree is a graphical object that estimates the pattern of dependencies created by the ancestral history of a set of observed sequences. A rich array of problems in the biological sciences revolve around the origination, differentiation, and evolution of important genes. Even crude methods of inference for phylogenetic trees have provided fundamental discoveries in everything from the origins of species, to the clinical, epidemiological and biological behavior of HIV, to the understanding of antibiotic resistance in bacteria. This session will highlight some of the exciting new work that has addressed complex statistical and computational issues while providing insight into these important biological problems.
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