Investigating Heterogeneity of Treatment Effect Using Propensity Scores in a Prospective Observational Study of the Comparative Effectiveness of Treatments for Glaucoma
View Presentation *Priscilla Velentgas, Quintiles Outcome Keywords: Heterogeneity, Comparative effectiveness, Glaucoma, Observational study, Propensity scores Stratification on the propensity score has been used to identify heterogeneity of treatment effect (HTE) and may be an indicator of clinically meaningful differences between subgroups. The RiGOR study, an AHRQ-funded prospective observational study of the comparative effectiveness of open angle glaucoma treatments, incorporates analysis of HTE across pre-specified minority subgroups. Recruitment and baseline data collection for RiGOR is complete. Follow-up for clinical outcomes over 12 months is ongoing. Results of estimation of propensity scores indicative of treatment preference and heterogeneity in the propensity score between two or more minority subgroups in RiGOR will be presented. Implications for the final analyses comparing clinical outcomes according to treatment will be explored.
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Key Dates
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April 30 - May 22, 2013
Invited Abstract Submission Open -
June 4, 2013
Online Registration Opens -
August 9 - August 23, 2013
Invited Abstract Editing -
August 23, 2013
Short Course materials due from Instructors -
August 26, 2013
Housing Deadline -
September 9, 2013
Cancellation Deadline and Registration Closes @ 11:59 pm EDT -
September 16 - September 18, 2013
Marriott Wardman Park, Washington, DC