Monte Carlo Simulation for the Pharmaceutical Industry
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*Mark Chang, AMAG Pharmaceuticals 

Keywords: clinical trial simulation, adaptive design, decision theory, game theory, Markov decision process, dynamic programming

Give an overview of application of simulations to various aspects and stages of drug development. It will cover the following topics:

• Markov Decision Process and Game theory in Pharmaceutical R & D • Classical and Adaptive Clinical Trial Simulations • Simulation Dynamic Drug Supply • Simulation in Prescription Drug Commercialization • Disease Modeling and Biological Pathway Simulation, etc.

This talk will also describe a number of different simulation techniques. Clinical trial simulation will be the focus point for this talk.